Tuberculosis, Leprosy and Other Mycobacterial Diseases of Man and Animals

The Many Hosts of Mycobacteria

November 2015
More details
  • Publisher
  • Published
    16th November 2015
  • ISBN 9781780643960
  • Language English
  • Pages 580 pp.
  • Size 6.75" x 9.75"

Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV and the possible cross-infection of badgers and cattle associated with M. bovis. This ideal reference for researchers working in different fields draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.


Section 1: Tuberculosis in Humans
1. Introduction and epidemiology
2. Comparative Mycobacteriology of the M. tuberculosis complex
3. Immunopathogenesis of Tuberculosis in Humans
4. Current methods of diagnostics and Global Tuberculosis Surveillance
5. Current available strategies for Prevention and Intervention
6. Development of New Tuberculosis Vaccines
7. Molecular Epidemiology of M. tuberculosis and Evolution of Drug Resistance

Section 2: Tuberculosis in Domesticated & Companion Animal Species
8. Global Distribution of bovine TB and comparative genomics
9. Immunopathogenesis of M. bovis infection in cattle
10. Diagnosis of M. bovis Infection in Cattle
11. Vaccines and Biomarkers for M. bovis infection in cattle
12. M. bovis / M. caprae Infection in Goats and Sheep: Introduction, epidemiology and control measures
13. Mycobacterial Infections in Camelids
14. Tuberculosis in Companion Animal Species

Section 3: Mycobacterial Infections in Zoo Species
15. Mycobacterial Infection in Elephants
16. Mycobacterial Infections in Other Zoo species

Section 4: Tuberculosis in Wildlife
17. Tuberculosis in Badgers
18. Tuberculosis in Wild Boar and Domestic Pigs
19. Tuberculosis in Brushtail Possums
20. Tuberculosis in Deer – Captive and Free Ranging
21. Tuberculosis in South African Wildlife: Lions, Cape Buffalo and other species
22. Mycobacterium mungi in mongoose

Section 5: In vivo Laboratory Models of Tuberculosis
23. Rabbits
24. Guinea Pigs
25. Mice
26. Non-human Primates
27. Aerobiology

Section 6: Other Mycobacterial Diseases
28. Mycobacterium leprae in Humans
29. Mycobacterium leprae in other species (Armadillos /mice)
30. Mycobacterium avium subsp. paratuberculosis infection of livestock
31. Non-tuberculous mycobacterial infections

Harshini Mukundan

Harshini Mukundan is at the Los Alamos National Laboratory.

Mark Chambers

Mark Chambers is with Animal and Plant Health Agency (APHA), UK and School of Veterinary Medicine, University of Surrey, UK.

Ray Waters

Ray Waters is with USDA.

Michelle Larsen

Michelle Larsen teaches at the Albert Einstein College of Medicine.