Molecular Nutrition

August 2003
More details
  • Publisher
  • Published
    1st August 2003
  • ISBN 9780851996790
  • Language English
  • Pages 432 pp.
  • Size 6.875" x 9.75"

Molecular nutrition (the study of interactions between nutrients and various intracellular and extracellular molecules) is one of the most rapidly developing fields in nutritional science. Ultimately, molecular nutrition research will reveal how nutrients may affect fundamental processes such as DNA repair, cell proliferation, and apoptosis. This book is the only single complete volume available reviewing the field of molecular nutrition. It contains contributions from leading international experts, and reviews the most important and latest research from various areas of molecular nutrition.

"The editors need to be congratulated on selecting experts who have made important contributions in advancing our understanding of how nutrients and micronutrients may exert their effects in living cells and organisms. Molecular Nutrition offers an important reference for the student and the expert interested in obtaining answers to "how nutrients work."

- American Journal of Human Biology

"The book has achieved the almost impossible task of condensing the essential aspects of molecular nutrition. It is written in a clear and comprehensible style, which makes it a valuable introduction to this very important topic for anyone interested in or working in molecular nutrition. I will certainly keep a copy on my bookshelf."

- Scandinavian Journal of Nutrition

"The book should be a component of every nutrition scientist's library and teaching program."

- American Journal of Clinical Nutrition

Part 1: Methods in Molecular Nutrition Research
* Genomics and beyond
* Perspectives in postgenomic nutrition research

Part 2: Cellular Nutrient Homeostasis, Proliferation, and Apoptosis
* Molecular physiology of plasma membrane transporters for organic nutrients
* Intracellular trafficking and compartmentalization of vitamins and their physiologically active forms
* Nutrient homeostasis in proliferating cells
* Nutrients and apoptosis

Part 3: Roles for Nutrients in Signal Transduction
* Glucose regulation of gene expression in mammals
* Amino acid-dependent control of transcription in mammalian cells
* Fatty acids and gene expression
* Roles of RARs and RXRs in mediating the molecular mechanism of action of vitamin A
* Regulation of gene expression by biotin
* Selenium and vitamin E
* Sphingolipids: a new strategy for cancer treatment and prevention
* The health effects of dietary isoflavones
* Mechanisms of ubiquitination and proteasome-dependent proteolysis in skeletal muscle

Part 4: Nucleic Acids and Nucleic Acid-binding Compounds
* Diet, DNA methylation and cancer
* Biotinylation of histones in human cells
* Niacin status, poly(ADP-ribose) metabolism and genomic instability

Part 5: Molecular Events Affect Physiology
* Assembly of triglyceride transporting plasma lipoproteins
* Regulation of cellular cholesterol
* 2002 Assessment of Nutritional Influences on Risk for Cataract
* Nutrition and immune function

Part 6: Foods
* Molecular mechanisms of food allergy
* Safety assessment of genetically modified foods

J  Zempleni

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H  Daniel

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