Protein Turnover

Hardback
May 2006
9780851996134
More details
  • Publisher
    CABI
  • Published
    26th May 2006
  • ISBN 9780851996134
  • Language English
  • Pages 320 pp.
  • Size 6.875" x 9.75"
$230.60

This book is concerned with protein metabolism at the physiological, not the molecular level and particularly with studies on human beings. Protein turnover is a vital function, no less important than oxygen turnover, because of this over the last 20 years there has been an increase in the research on protein turnover in man, with parallel work on farm animals. Methods that have been used for measuring whole body protein turnover in man, the underlying problems and assumptions and the problems that have been encountered are discussed in this comprehensive book.

Basic Principles
Models and their analysis
Free amino acids: their pools, kinetics and transport
Metabolism of some amino acids
The precursor problem
Whole body protein turnover measured by the precursor method
Measurement of whole body protein turnover by the end-product method
Amino acid oxidation and urea metabolism
The effects of food and hormones on protein turnover in the whole body and regions
Adaptation to different protein intakes: Protein and amino acid requirements
Physiological determinants of protein turnover
Whole body protein turnover during growth and in pregnancy and lactation
Whole body protein turnover in some pathological states
Tissue protein turnover
Protein synthesis in individual tissues and the effects of food and hormones
Turnover of plasma proteins
Collagen turnover
Mechanisms of synthesis and breakdown

J C  Waterlow

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