Parasitic Flatworms

Molecular Biology, Biochemistry, Immunology and Physiology

Hardback
June 2006
9780851990279
More details
  • Publisher
    CABI
  • Published
    16th June 2006
  • ISBN 9780851990279
  • Language English
  • Pages 480 pp.
  • Size 6.875" x 9.75"
$278.25

Parasitic flatworms include Cestodes (tapeworms) and trematodes (flukes, schistosomes, etc), and are the cause of a number of major diseases of medical and veterinary significance. Much recent research has focused on molecular biology and genomics. this book aims to review advances in our understanding of these and related topics such as flatworm biochemistry, immunology and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-living species. Contributors to the book include leading authorities from Europe, North and South America, and Australia.

Part I: Phylogeny, Genetics and Transcriptomes
The Evolution of Parasitism in Flatworms
Genomes and Genomics of Parasitic Flatworms
Genetic Discrimination of Echinococcus Species and Strains
Ribosomal DNA Variation in Parasitic Flatworms
Genetic Studies on Monogeneas with Emphasis on Gyrodactylus
The Schistosome Transcriptome
Transgenic Flatworms

Part II: Immunobiology, Host-Parasite Interaction and Control
Immunobiology of Schistosomes
Cestode Infection: Immunological Considerations From Host and Tapeworm Perspectives
Parasitic Flatworms: Signal Transduction at the Host-Parasite Interface
Parasite Effects on the Snail Host Transcriptome
Developments in the chemotherapy of parasitic flatworms
Drug Resistance in Schistosomes
Praziquantel: Mechanism of Action
Cestode Vaccine Development
The Development of a Schistosome Vaccine

Part III: Protein Function, Metabolism and Physiology
Flatworm Parasite Proteomics
Proteases in Trematode Biology
Signalling Molecules and Nerve-Muscle Function
Unusual Aspects of Metabolism in Flatworm Parasites
Glycoconjugate Structures
Gene Silencing in Flatworms using RNA interference

Aaron G Maule

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Nikki J Marks

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