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Chlamydiae and Chlamydial Infections

Hardback
May 2018
9788793609518
More details
  • Publisher
    River Publishers
  • Published
    15th May 2018
  • ISBN 9788793609518
  • Language English
  • Pages 225 pp.
  • Size 6.125" x 9.5"
$110.00
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May 2018
9788793609501
More details
  • Publisher
    River Publishers
  • Published
    15th May 2018
  • ISBN 9788793609501
  • Language English
  • Pages 225 pp.
$82.50

Chlamydiae are a group of obligate intracellular microorganisms with a homogeneous group-specific antigenic structure, and a unique mode of development. The infections caused by them are unprecedented and wide-spread throughout the world, including a broad range of hosts among domestic and animal species and humans, and a variety of clinical manifestations. The uniqueness of chlamydia pathology consists mainly in the fact that the agents of the individual diseases are so close in their biological properties that they are represented only by the single genus Chlamydia, which includes all currently recognized species.

Although chlamydiae and chlamydial infections were discovered a long time ago, they are still under-researched and relatively unknown to broad circles of microbiologists, virologists, epidemiologists and clinicians. A number of issues relating to molecular biology, pathogenesis, mechanisms of Chlamydia development and their interactions with cells, as well as their genetic conditioning and regulation, remain unclear. The same is true for ambiguities, problems and contradictions related to epidemiology, diagnostic approaches, immunity and vaccines. Based on scientific facts and the analysis of literature, and the experience of the author, Chlamydiae and Chlamydial Infections attempts to shed light on the cited problems, in terms of modern microbiology, cell biology and molecular biology. The scientific topics discussed include:

- Biological, morphological and antigenic properties of Chlamydia spp
- Genes, genomic structure and genetic regulations
- Conventional diagnostic methods and examinations
- Detection and differentiation of Chlamydia organisms by DNA detection systems
- Clinical forms and manifestations and drug therapy
- Pathology
- Epidemiological peculiarities of Chlamydia - induced diseases in animals and humans
- Immunity and vaccines.

Preface
Introduction

1. Historical Notes
2. Nature of Chlamydia Organisms and Taxonomy
3. Morphology, mode of development, interaction with the cells
4. Genomic structure, Genes, Molecular regulation of the development of Chlamydiae
5. Isolation and cultivation of Chlamydia
6. Virulence and pathogenicity
7. Chlamydial antigens and antigenic analysis
8. Immunity and antibodies
9. Serology
10. Detection and differentiation of Chlamydia microorganisms by DNA detection systems
11. Clinical Picture
12. Pathology
13. Epidemiology
14. Vaccines for Chlamydia-induced diseases
Bibliography
Keyword Index

Svetoslav P. Martinov

Svetoslav P. Martinov is with the National Diagnostic and Research Veterinary Medical Institute in Sofia, Bulgaria.