CABI Biotechnology Series Series 3

Transgenic Insects

Techniques and Applications

November 2019
More details
  • Publisher
  • Published
    8th November 2019
  • ISBN 9781786395436
  • Language English
  • Pages 388 pp.
  • Size 6" x 9"
  • Images graphs, b/w & color illus and photos
December 2014
More details
  • Publisher
  • Published
    5th December 2014
  • ISBN 9781780644516
  • Language English
  • Pages 388 pp.
  • Size 6" x 9"
  • Images graphs, b/w & color illus and photos

Insect transgenesis promises improvements in agriculture, pharmaceuticals and public health. Many important insects can now be routinely transformed with effectors that have useful applications. Agriculture presents the largest market for transgenic insects and has a foundational history of success with sterile insect technique for control of pests including Mediterranean fruit flies and screwworms. Biotechnology will contribute superior markers, suppressible sterility and sex-conversion. Public health is also seeing transgenic mosquitoes developed which suppress natural populations and are incapable of transmitting disease. In this book, exprts in the field will contribute their insights into the latest technology and its applications and consider the larger risks, social and economic aspects of transgenic insects whose value must be proven in political, regulatory and public acceptance arenas.

Germline Transformation Technology
1) Transposons for Insect Transformation
2) Transposon-based Technologies for Insects
3) Sex-, Tissue- and Stage-Specific Transgene Expression
4) Docking Systems for Site-Directed Transgene Integration
5) Inducible and Repressible Systems for Transgene Expression

Applications of Transgenic Insects
6) Sex Ratio Manipulation for Insect Population Control
7) Conditional Dominant Lethals – RIDL
8) Tephritid Fruit Fly Transgenesis and Applications
9) Silkworm Transgenesis and Applications
10) Transgenic Approaches for Sterile Insect Control of Dipteran Livestock Pests and Lepidopteran Crop Pests
11) Anti-Pathogen Effector Molecules: Current and Future Strategies
12) Sexual Sterilization of Mosquitoes

Alternative Transgenic Approaches to Modifying Insect Phenotypes
13) Paratransgenesis in Mosquitoes and Other Insects: Microbial Ecology and Bacterial Genetic Considerations
14) Asaia Paratrangenesis in Mosquitoes
15) Paratransgenic Control of Chagas Disease
16) Tsetse Paratransgenesis: A Novel Strategy for Reducing the Spread of African Trypanosomiases

Considerations for the Release of Transgenic Insects
17) RIDL: Modelling Release of Insects Carrying a Dominant Lethal
18) Assessing Risk of Transgenic Insects
19) Economics of Transgenic Insects for Field Release
20) Risk Analysis and the Regulation of Transgenic Insects
21) Public Acceptability of New Insect Vector Control Technologies
22) The Cartagena Protocol on the Transboundary Movement of Living Modified Organisms

Regulation of Trade in Transgenic Organisms Under International and European Environmental Law

Mark Quentin Benedict

Mark Quentin Benedict has a PhD in entomology with an emphasis on molecular biology and genetics from the University of Florida. He has developed technology for the development of transgenic insects; developed insectary methods for producing mosquitoes for release into the field; directed field studies underlying releases of transgenic insects; and assisted developing country operations where transgenic insects will be used. He has worked at USDA, the Centers for Disease Control and Prevention (CDC), the International Atomic Energy Agency and the University of Perugia. He is currently a research biologist at the CDC and is based in Atlanta, GA. He has contributed book chapters and over 100 peer reviewed publications.